New echocardiographic parameters in the diagnosis of heart failure with preserved ejection fraction

Heart failure with preserved ejection fraction (HFpEF) is a serious clinical disease. The pathophysiology of HFpEF is complex, and specific diagnostic criteria have evolved over time. Limited data are available on the quantification of diastolic function using two-dimensional real-time echocardiogra...

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Bibliographic Details
Published in:The International Journal of Cardiovascular Imaging 2018-02, Vol.34 (2), p.229-235
Main Authors: Špinarová, Monika, Meluzín, Jaroslav, Podroužková, Helena, Štěpánová, Radka, Špinarová, Lenka
Format: Article
Language:English
Subjects:
Aged
Biomechanical Phenomena
Cardiac Imaging
Cardiology
Criteria
Diagnosis
Diagnostic systems
Dyspnea
Echocardiography
Echocardiography, Doppler
Ejection fraction
Female
Heart diseases
Heart failure
Heart Failure - diagnostic imaging
Heart Failure - physiopathology
Humans
Imaging
Male
Medicine
Medicine & Public Health
Middle Aged
Models, Cardiovascular
Multivariate Analysis
Myocardial Contraction
Original Paper
Patients
Predictive Value of Tests
Prognosis
Radiology
Respiration
Retrospective Studies
Stroke Volume
Ultrasonic imaging
Ventricular Function, Left
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Summary:Heart failure with preserved ejection fraction (HFpEF) is a serious clinical disease. The pathophysiology of HFpEF is complex, and specific diagnostic criteria have evolved over time. Limited data are available on the quantification of diastolic function using two-dimensional real-time echocardiography, and a simple parameter has not yet been established. The aim of this work is to evaluate new echocardiographic parameters—the diastolic wall strain of the posterior wall (DWS PW) and the vortex formation time (VFT). Echocardiographic data from 111 subjects with exertional dyspnea and normal left ejection fraction (Group A) and 20 healthy volunteers (Group B) were retrospectively evaluated. In addition to the standard parameters used in the diagnosis of HFpEF, DWS PW and VFT were assessed in all patients. HFpEF was diagnosed in 38 patients with dyspnea (Group A1). The remaining 73 patients did not meet the established criteria for a positive diagnosis of HFpEF (Group A2). We discovered that both observed parameters were significantly lower in patients with HFpEF than in other groups. Multivariate analysis revealed that both DWS PW and VFT independently predicted the presence of HFpEF. DWS PW and VFT are simple parameters in the evaluation of diastolic function and may play a potential role as a part of an integrated approach to the assessment of HFpEF.
ISSN:1569-5794
1573-0743
1875-8312
DOI:10.1007/s10554-017-1230-z