Neonatal intoxication to vitamin D in premature babies: A series of 16 cases

Preterm neonates are particularly at risk of vitamin D (25-D) deficiency. To prevent rickets and osteopenia in this population, international guidelines vary between 800 and 1000IU per day of vitamin D in Europe and recommend 400IU per day in the USA. Target levels of circulating 25-D are not well i...

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Bibliographic Details
Published in:Archives de pédiatrie : organe officiel de la Société française de pédiatrie 2017-09, Vol.24 (9), p.817-824
Main Authors: Vierge, M, Laborie, S, Bertholet-Thomas, A, Carlier, M-C, Picaud, J-C, Claris, O, Bacchetta, J
Format: Article
Language:fre
Subjects:
Drug Overdose
Female
Humans
Hypercalcemia - chemically induced
Hypercalciuria - chemically induced
Infant, Newborn
Infant, Premature
Male
Nephrocalcinosis - chemically induced
Retrospective Studies
Vitamin D - poisoning
Vitamins - poisoning
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Summary:Preterm neonates are particularly at risk of vitamin D (25-D) deficiency. To prevent rickets and osteopenia in this population, international guidelines vary between 800 and 1000IU per day of vitamin D in Europe and recommend 400IU per day in the USA. Target levels of circulating 25-D are not well identified, with the lower target level 50-75nmol/L and the upper target level probably 120nmol/L. Between 2013 and 2015, 16 premature infants (born
ISSN:1769-664X
DOI:10.1016/j.arcped.2017.06.016