Severe osteoarticular infection associated with Panton-Valentine leukocidin-producing Staphylococcus aureus

We report here a case of osteoarticular infection associated with Panton-Valentine leukocidin-producing Staphylococcus aureus. The 3-year-old child presented osteoarthritis associated with toxic shock syndrome, which was complicated by thrombosis, pneumonia, and diaphysitis, despite appropriate anti...

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Bibliographic Details
Published in:Diagnostic microbiology and infectious disease 2006-09, Vol.56 (1), p.95-97
Main Authors: Moumile, Kaoutar, Cadilhac, Céline, Lina, Gérard, Berche, Patrick, Glorion, Christophe, Ferroni, Agnès
Format: Article
Language:English
Subjects:
Arthritis, Infectious - complications
Arthritis, Infectious - microbiology
Arthritis, Infectious - surgery
Bacterial Toxins - adverse effects
Bacterial Toxins - metabolism
Bacteriology
Biological and medical sciences
Child, Preschool
Drug Resistance, Bacterial
Exotoxins - adverse effects
Exotoxins - metabolism
Femur - microbiology
Fundamental and applied biological sciences. Psychology
Humans
Infectious diseases
Leukocidins
Male
Medical sciences
Microbiology
Miscellaneous
Osteoarthritis - complications
Osteoarthritis - microbiology
Osteoarthritis - surgery
Osteoarticular infection
Panton-Valentine leukocidin
Shock, Septic - microbiology
Staphylococcal Infections - complications
Staphylococcal Infections - pathology
Staphylococcal Infections - surgery
Staphylococcus aureus
Staphylococcus aureus - drug effects
Staphylococcus aureus - metabolism
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Summary:We report here a case of osteoarticular infection associated with Panton-Valentine leukocidin-producing Staphylococcus aureus. The 3-year-old child presented osteoarthritis associated with toxic shock syndrome, which was complicated by thrombosis, pneumonia, and diaphysitis, despite appropriate antibiotic treatment. Osteitis associated with toxinogenic S. aureus is rarely described. This case highlights the need of early and aggressive surgical treatment, in addition to appropriate antimicrobial therapy.
ISSN:0732-8893
1879-0070
DOI:10.1016/j.diagmicrobio.2006.03.007