Neurostimulation Therapy for Non-neurogenic Overactive Bladder in Children: A Meta-analysis

To assess the efficacy and safety of neurostimulation for non-neurogenic overactive bladder in children, we conducted a meta-analysis of randomized controlled trials (RCTs). A systematic literature search was performed on August 2016. RCTs were evaluated according to the Cochrane Collaboration risk...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2017-12, Vol.110, p.201-207
Main Authors: Fernandez, Nicolas, Chua, Michael E., Ming, Jessica M., Silangcruz, Jan Michael, Zu'bi, Fadi, Dos Santos, Joana, Lorenzo, Armando J., Braga, Luis H., Lopes, Roberto Iglesias
Format: Article
Language:English
Subjects:
Child
Electric Stimulation Therapy
Humans
Randomized Controlled Trials as Topic
Urinary Bladder, Overactive - therapy
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Summary:To assess the efficacy and safety of neurostimulation for non-neurogenic overactive bladder in children, we conducted a meta-analysis of randomized controlled trials (RCTs). A systematic literature search was performed on August 2016. RCTs were evaluated according to the Cochrane Collaboration risk of bias assessment. Number of patients with post-treatment partial response (PR) (50%-89%), complete response (CR) (≥90%), and full response (FR) (100%) were extracted for relative risk (RR) and 95% confidence interval (CI). Effect estimates were pooled using the Mantel-Haenszel method with random effect model if significant inter-study heterogeneity (P 
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2017.08.003