Quality of life after thyroidectomy in patients with nontoxic nodular goiter: A prospective cohort study

Background Using the thoroughly validated Thyroid‐Related Quality‐of‐Life Patient‐Reported Outcome (ThyPRO) questionnaire, the purpose of this study was to investigate changes in disease‐specific quality of life (QOL) after surgical treatment in patients with benign nontoxic multinodular goiters. Me...

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Bibliographic Details
Published in:Head & neck 2017-11, Vol.39 (11), p.2232-2240
Main Authors: Sorensen, Jesper Roed, Watt, Torquil, Cramon, Per, Døssing, Helle, Hegedüs, Laszlo, Bonnema, Steen Joop, Godballe, Christian
Format: Article
Language:English
Subjects:
Adult
Aged
Anxiety
Anxiety - etiology
Anxiety - prevention & control
Benign
Cohort analysis
Cohort Studies
Denmark
Disorders of Excessive Somnolence - etiology
Disorders of Excessive Somnolence - prevention & control
Female
Goiter
Goiter, Nodular - complications
Goiter, Nodular - psychology
Goiter, Nodular - surgery
Head and neck
Health risk assessment
Humans
Male
Middle Aged
Patient Reported Outcome Measures
Population
Population studies
Quality of Life
Surgery
Thyroid
Thyroid gland
Thyroidectomy
Thyroid‐Related Quality‐of‐Life Patient‐Reported Outcome (ThyPRO)
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Summary:Background Using the thoroughly validated Thyroid‐Related Quality‐of‐Life Patient‐Reported Outcome (ThyPRO) questionnaire, the purpose of this study was to investigate changes in disease‐specific quality of life (QOL) after surgical treatment in patients with benign nontoxic multinodular goiters. Method Patients with goiters scheduled for thyroid surgery (n = 106) and individuals from the general population (n = 739) were studied. The ThyPRO data before, 3 months, and 6 months after surgery were compared with normative scores from the general population using a linear mixed model and t tests. Results Before surgery, patients with goiters experienced poorer scores on all scales compared to the general population. After surgery, moderate to large improvements were seen in goiter symptoms, tiredness, anxiety, and overall QOL. After surgery, all scales returned to values equal to the general population. The degree of anxiety was, in fact, lower than in the general population. Conclusion Thyroid surgery leads to significant benefit among patients with benign nontoxic goiters by restoring QOL equal to that in the general population.
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.24886