Very low LDL-cholesterol concentrations achieved: which target is next?

It has been a long and winding road towards acceptance of LDL cholesterol as a pivotal and causal factor in the development of atherosclerosis and cardiovascular disease. The evidence was first derived from experimental, epidemiological, and genetic studies, as well as from clinical trials with stat...

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Bibliographic Details
Published in:The Lancet (British edition) 2017-10, Vol.390 (10106), p.1930-1931
Main Authors: Hovingh, G Kees, Boekholdt, S Matthijs, Stroes, Erik S
Format: Article
Language:English
Subjects:
Atherosclerosis
Cardiovascular disease
Cardiovascular diseases
Cholesterol
Fees & charges
Health risk assessment
Health risks
Lipids
Low density lipoprotein
Monoclonal antibodies
Proprotein convertases
Public speaking
Statins
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Summary:It has been a long and winding road towards acceptance of LDL cholesterol as a pivotal and causal factor in the development of atherosclerosis and cardiovascular disease. The evidence was first derived from experimental, epidemiological, and genetic studies, as well as from clinical trials with statins and ezetimibe.1
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(17)32292-4