Silver diamine fluoride remineralized artificial incipient caries in permanent teeth after bacterial pH-cycling in-vitro

To investigate the remineralizing effect of 38% silver diamine fluoride (SDF) application on enamel artificial caries in adjunct to 1000ppm fluoride toothpaste compared with fluoride toothpaste alone by analyzing the mineral density, depth of remineralization, and remineralization percentage of the...

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Bibliographic Details
Published in:Journal of dentistry 2018-02, Vol.69, p.55-59
Main Authors: Punyanirun, Kulnipa, Yospiboonwong, Thanida, Kunapinun, Thansinee, Thanyasrisung, Panida, Trairatvorakul, Chutima
Format: Article
Language:English
Subjects:
Artificial caries
Cariostatic Agents - pharmacology
Cariostatic Agents - therapeutic use
Clinical trials
Dental caries
Dental Caries - pathology
Dental Caries - prevention & control
Dental Enamel - diagnostic imaging
Dental Enamel - drug effects
Dental Enamel - pathology
Dentistry
Enamel
Fluoridation
Fluoride treatments
Fluorides
Fluorides - pharmacology
Fluorides - therapeutic use
Fluorides, Topical - pharmacology
Fluorides, Topical - therapeutic use
Humans
Hydrogen-Ion Concentration
Incipient caries
Lesions
Mineral density
Minerals - analysis
Oral hygiene
Permanent teeth
Quaternary Ammonium Compounds - pharmacology
Quaternary Ammonium Compounds - therapeutic use
Remineralization
Silver Compounds - pharmacology
Silver Compounds - therapeutic use
Silver diamine fluoride
Sodium Fluoride - pharmacology
Sodium Fluoride - therapeutic use
Streptococcus mutans
Teeth
Tooth Remineralization - methods
Toothpaste
Toothpastes - chemistry
Toothpastes - therapeutic use
X-Ray Microtomography
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Summary:To investigate the remineralizing effect of 38% silver diamine fluoride (SDF) application on enamel artificial caries in adjunct to 1000ppm fluoride toothpaste compared with fluoride toothpaste alone by analyzing the mineral density, depth of remineralization, and remineralization percentage of the lesions. Eighteen artificial caries slabs were created from the proximal surfaces of nine chemically demineralized premolars. The slabs were scanned by Micro-Computed Tomography (Micro-CT) to determine the baseline mineral density of the initial lesions and randomly allocated into 2 groups. The test group was applied with 38% SDF in adjunct to fluoride toothpaste and the control group was treated with fluoride toothpaste alone. The specimens underwent bacterial pH-cycling for 5 d and were re-evaluated using Micro-CT. The pre-treatment and post-treatment mineral densities were plotted and the areas under the curves were used to calculate the remineralization percentage of both groups. Mineral density significantly increased in both groups after pH-cycling (p
ISSN:0300-5712
1879-176X
DOI:10.1016/j.jdent.2017.09.005