Chitin and chitosan preparation from shrimp shells Penaeus monodon and its human ovarian cancer cell line, PA-1

In the present study, chitin and chitosan preparation from shrimp shells Penaeus mondon and its ovarian cancer cell line (PA-1). FTIR spectrum sharp absorption peak at 1655cm−1 is assigned to ketone C=O (α) unsaturated with chitosan. X-ray diffraction showed the presence of chitin and chitosan were...

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Bibliographic Details
Published in:International journal of biological macromolecules 2018-02, Vol.107 (Pt A), p.662-667
Main Authors: Srinivasan, Haripriya, Kanayairam, Velayutham, Ravichandran, Ramanibai
Format: Article
Language:English
Subjects:
Animal Shells - chemistry
Animals
Antineoplastic Agents - isolation & purification
Antineoplastic Agents - pharmacology
Antioxidants - isolation & purification
Antioxidants - pharmacology
Biphenyl Compounds - antagonists & inhibitors
Cell Line, Tumor
Cell Survival - drug effects
Chitin
Chitin - isolation & purification
Chitin - pharmacology
Chitosan
Chitosan - isolation & purification
Chitosan - pharmacology
Female
FTIR
Humans
Ovary - drug effects
Ovary - pathology
Penaeidae - chemistry
Penaeus monodon
Picrates - antagonists & inhibitors
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Summary:In the present study, chitin and chitosan preparation from shrimp shells Penaeus mondon and its ovarian cancer cell line (PA-1). FTIR spectrum sharp absorption peak at 1655cm−1 is assigned to ketone C=O (α) unsaturated with chitosan. X-ray diffraction showed the presence of chitin and chitosan were strongest peak at 18.91° (β) and 29.75° (α) characters. SEM observations of chitin and chitosan surface morphologies of P. monodon showed that microfibril and porous structures. Anticancer activity of chitin and chitosan against human ovarian cancer cell line showed that chitosan an exhibited notable higher activity than chitin. Anticancer activity of aquacultural waste of shrimp shells mediated chitosan, which was proved to be good novel pharmaceutical industries.
ISSN:0141-8130
1879-0003
DOI:10.1016/j.ijbiomac.2017.09.035