Incidence, Prevalence, Etiology, and Prognosis of First-Time Chronic Pancreatitis in Young Patients: A Nationwide Cohort Study

Background/Aims Publications on etiology of chronic pancreatitis (CP) are infrequent. Etiologies today encompass genetic disorders. We wanted to describe etiologies of today and identify patients with genetic disorders like hereditary pancreatitis (HP), mutations in Serine Protease Inhibitor Kazal t...

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Bibliographic Details
Published in:Digestive diseases and sciences 2010-10, Vol.55 (10), p.2988-2998
Main Authors: Joergensen, Maiken, Brusgaard, Klaus, Crüger, Dorthe Gylling, Gerdes, Anne-Marie, de Muckadell, Ove B. Schaffalitzky
Format: Article
Language:English
Subjects:
Acute Disease
Adolescent
Adult
Age Distribution
Analysis
Biochemistry
Biological and medical sciences
Cause of Death
Causes and theories of causation
Chronic Disease
Cohort Studies
Comorbidity
Cystic fibrosis
Denmark - epidemiology
Development and progression
Diseases
Exocrine Pancreatic Insufficiency - etiology
Exocrine Pancreatic Insufficiency - mortality
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Gallstones
Gastroenterology
Gastroenterology. Liver. Pancreas. Abdomen
Gene mutations
Genetic aspects
Health aspects
Hepatology
Hospitalization - statistics & numerical data
Humans
Incidence
Kaplan-Meier Estimate
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical research
Medical sciences
Medicine
Medicine & Public Health
Medicine, Experimental
Oncology
Original Article
Other diseases. Semiology
Pancreatitis
Pancreatitis, Alcoholic - etiology
Pancreatitis, Alcoholic - mortality
Pancreatitis, Chronic - etiology
Pancreatitis, Chronic - mortality
Prevalence
Prognosis
Protease inhibitors
Registries - statistics & numerical data
Sex Distribution
Thrombin
Transplant Surgery
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Young Adult
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Summary:Background/Aims Publications on etiology of chronic pancreatitis (CP) are infrequent. Etiologies today encompass genetic disorders. We wanted to describe etiologies of today and identify patients with genetic disorders like hereditary pancreatitis (HP), mutations in Serine Protease Inhibitor Kazal type1 ( SPINK1 ), and the Cystic Fibrosis Transmembrane Conductance Regulator gene (C FTR ) among patients formerly considered to have idiopathic CP. Methods Data on patients diagnosed with first-time CP 
ISSN:0163-2116
1573-2568
DOI:10.1007/s10620-009-1118-4