Evaluation of Cardiac Function by Two-Dimensional Speckle Tracking Echocardiography in Ulcerative Colitis Patients

Purpose Although ulcerative colitis (UC) shows obvious similarities with other autoimmune diseases, cardiac consequences have not adequately introduced. The aim of our study was to evaluate left ventricular (LV) function in UC patients by using novel echocardiographic parameters. Results Forty-five...

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Bibliographic Details
Published in:Digestive diseases and sciences 2014-12, Vol.59 (12), p.3004-3011
Main Authors: Cincin, Altug, Sunbul, Murat, Kivrak, Tarık, Atas, Halil, Sari, Ibrahim, Tigen, Kursat, Kani, Tarik, Akin, Hakan, Imeryuz, Nese, Basaran, Yelda
Format: Article
Language:English
Subjects:
Adalimumab
Adult
Analysis
Biochemistry
Case-Control Studies
Colitis, Ulcerative - complications
Echocardiography
Echocardiography - methods
Female
Gastroenterology
Heart
Hepatology
Humans
Male
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
Middle Aged
Oncology
Original Article
Transplant Surgery
Ulcerative colitis
Ventricular Function, Left - physiology
Young Adult
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Summary:Purpose Although ulcerative colitis (UC) shows obvious similarities with other autoimmune diseases, cardiac consequences have not adequately introduced. The aim of our study was to evaluate left ventricular (LV) function in UC patients by using novel echocardiographic parameters. Results Forty-five UC patients (mean age 37, 18 female) and 90 age- and sex-matched healthy volunteers (mean age 40, 38 female) included in the study. The mean disease activity score according to partial Mayo score was 2.16 ± 2.13. Mean global longitudinal strain (GLS) and global longitudinal strain rate (GLSR) measurements were significantly lower (−21.16 ± 2.71 vs. −23.36 ± 3.34; p  
ISSN:0163-2116
1573-2568
DOI:10.1007/s10620-014-3274-4