The haemostatic efficacy and foreign body reaction of epinephrine–Impregnated polyurethane foam in osseous defects

The objective of this study was to compare the haemostatic efficacy and foreign body reaction of epinephrine–impregnated cotton pellets with those of epinephrine‐impregnated polyurethane (PU) foam cubes in osseous defects created in guinea pigs. Initially, these substances were randomly applied to t...

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Bibliographic Details
Published in:Australian endodontic journal 2018-12, Vol.44 (3), p.204-207
Main Authors: Torabinejad, Mahmoud, Kang, Hyun J. S., Maskiewicz, Richard, Grandhi, Anupama
Format: Article
Language:English
Subjects:
Animals
apical surgery
Chi-Square Distribution
Cotton
Data processing
Defects
Dental Implantation, Endosseous, Endodontic - adverse effects
Dental Implantation, Endosseous, Endodontic - methods
Dentistry
Disease Models, Animal
Endodontics
Epinephrine
Epinephrine - administration & dosage
foam
foreign body reaction
Foreign-Body Reaction - therapy
Guinea Pigs
haemostatic
Hemorrhage - prevention & control
Hemostatic Techniques
impregnated polyurethane
Male
Polyurethane
Polyurethanes
Random Allocation
Surgery
Surgical Sponges
Treatment Outcome
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Summary:The objective of this study was to compare the haemostatic efficacy and foreign body reaction of epinephrine–impregnated cotton pellets with those of epinephrine‐impregnated polyurethane (PU) foam cubes in osseous defects created in guinea pigs. Initially, these substances were randomly applied to the osseous defects in guinea pigs for 2 min and blood loss was measured. The animals were then sacrificed 7 weeks later and the degree of foreign body reaction was scored. The data were analysed by the independent‐samples Kruskal‐Wallis test. Epinephrine‐impregnated PU foam cubes showed significantly better haemostatic effect compared to epinephrine–impregnated cotton pellets. The PU foam containing epinephrine specimens elicited significantly less foreign body reaction compared to epinephrine cotton pellets (P 
ISSN:1329-1947
1747-4477
DOI:10.1111/aej.12234