Circumferential margin involvement after total mesorectal excision for mid or low rectal cancer: are all R1 resections equal?

Aim Our aim was to assess the prognostic influence of the circumferential resection margin (CRM) exact value after total mesorectal excision for mid or low rectal cancer. Methods All patients (n = 321) who underwent total mesorectal excision from 2005 to 2013 were identified from a prospective datab...

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Bibliographic Details
Published in:Colorectal disease 2017-11, Vol.19 (11), p.O377-O385
Main Authors: Beaufrère, A., Guedj, N., Maggiori, L., Patroni, A., Bedossa, P., Panis, Y.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Cancer
circumferential margin involvement
circumferential margin resection
Colorectal cancer
Disease-Free Survival
Female
Follow-Up Studies
Humans
locoregional disease‐free survival
Male
Margins of Excision
Medical prognosis
Middle Aged
Multivariate Analysis
Neoplasm Recurrence, Local - etiology
Neoplasm Recurrence, Local - pathology
Neoplasm Staging
Postoperative Period
Prognosis
Proportional Hazards Models
Prospective Studies
Rectal cancer
Rectal Neoplasms - pathology
Rectal Neoplasms - surgery
Rectum
Rectum - pathology
Rectum - surgery
Regression Analysis
Retrospective Studies
Surgery
Survival
Treatment Outcome
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Summary:Aim Our aim was to assess the prognostic influence of the circumferential resection margin (CRM) exact value after total mesorectal excision for mid or low rectal cancer. Methods All patients (n = 321) who underwent total mesorectal excision from 2005 to 2013 were identified from a prospective database, including 49 (15%) who presented with a CRM ≤ 1 mm. Four groups were defined: group 1, CRM = 0 mm (n = 21); group 2, 0 
ISSN:1462-8910
1463-1318
DOI:10.1111/codi.13895