Comparison of embryo morphokinetics following intracytoplasmic sperm injection in smoker and non-smoker couples: Are the results different?

To assess early embryo development via time-lapse in smokers and non-smokers. The retrospective study was conducted at Novafertil IVF centers in Konya, Turkey and comprised oocytes of both smoker and non-smoker couples subjected to in vitro fertilisation / introcytoplasmic sperm injection from 2012...

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Bibliographic Details
Published in:Journal of the Pakistan Medical Association 2017-10, Vol.67 (10), p.1552-1557
Main Authors: Salvarci, Ahmet, Gurbuz, Ali Sami, Uzman, Sukru, Kaya, Melek, Gorkemli, Huseyin
Format: Article
Language:English
Subjects:
Comparative analysis
Embryo
Embryonic development
Follicle-stimulating hormone
Smokers
Sperm
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Summary:To assess early embryo development via time-lapse in smokers and non-smokers. The retrospective study was conducted at Novafertil IVF centers in Konya, Turkey and comprised oocytes of both smoker and non-smoker couples subjected to in vitro fertilisation / introcytoplasmic sperm injection from 2012 to 2015. Age, basal follicle-stimulating hormone, number of stimulation days, amount of gonadotropin used, number of metaphase II oocytes, number of embryos transferred and pregnancy, abortus and clinical pregnancy rates were noted. The embryos were observed for 72 hours in the time-lapse monitoring system. SPSS 22 was used for data analysis. Of the 257 couples, 132(51.4%) were non-smokers and 125(48.6%) were smokers. A total of 1,414 oocytes were collected from non-smokers and 1,280 oocytes from smokers. There was no significant difference in the age of patients and number of stimulation days between the smoker and non-smoker groups (p>0.05). The number of oocytes, fertilised oocytes, transferred embryos and metaphase II oocytes was significantly less in the smoker group (p
ISSN:0030-9982