Autologous transplantation of CD133 super(+) BM-derived stem cells as a therapeutic option for dilatative cardiomyopathy

We report the case of a 58-year-old man with end-stage non-ischemic cardiomyopathy. Baseline transthoracic echocardiography (TTE) and cardiac magnetic resonance (cMRI) revealed a markedly depressed left ventricle systolic function. He underwent autologous CD133 super(+) BM-derived cell transplantati...

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Bibliographic Details
Published in:Cytotherapy (Oxford, England) England), 2006-05, Vol.8 (3), p.308-310
Main Authors: Ghoclsizad, A, Ruhparwar, A, Marktanner, R, Borowski, A, Hasani, M M, Poll, L, Vshivkov, I, Stoldt, V, Voelkel, T, Piechaczek, C, Burchardt, E, Stockschlaeder, M, Sucker, C, Gams, E, Klein, H
Format: Article
Language:English
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Summary:We report the case of a 58-year-old man with end-stage non-ischemic cardiomyopathy. Baseline transthoracic echocardiography (TTE) and cardiac magnetic resonance (cMRI) revealed a markedly depressed left ventricle systolic function. He underwent autologous CD133 super(+) BM-derived cell transplantation through a minimally invasive approach. During surgery 19x10 super(6) BM-derived stem cells were injected by the transepimyocardial route. Six months after the operation TTE and cMRI showed a clear improvement in left ventricular contractility.
ISSN:1465-3249
DOI:10.1080/14653240600735909