The relationship between lymphocyte-to-monocyte ratio and saphenous vein graft patency in patients with coronary artery bypass graft

A lower lymphocyte count and a high monocyte count give important clues about the prognosis of various cardiovascular diseases. We hypothesized that lymphocyte-to-monocyte ratio (LMR) was associated with the saphenous vein graft disease (SVGD) in patients with coronary artery bypass graft (CABG). A...

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Bibliographic Details
Published in:Biomarkers in medicine 2017-10, Vol.11 (10), p.867-876
Main Authors: Oksuz, Fatih, Elcik, Deniz, Yarlioglues, Mikail, Duran, Mustafa, Ozturk, Selcuk, Celik, Ibrahim Etem, Kurtul, Alparslan, Kilic, Alparslan, Murat, Sani Namik
Format: Article
Language:English
Subjects:
Aged
Angina
Angiography
Area Under Curve
Atherosclerosis
Blood Glucose - analysis
Cardiovascular disease
Cardiovascular diseases
Cell number
Cholesterol, HDL - blood
Coronary Angiography
Coronary artery
Coronary Artery Bypass
coronary artery bypass graft
Female
Heart surgery
Humans
inflammation
Logistic Models
lymphocyte-to-monocyte ratio
Lymphocytes
Lymphocytes - cytology
Male
Medical imaging
Middle Aged
Monocytes
Monocytes - cytology
Odds Ratio
Retrospective Studies
ROC Curve
Saphenous Vein - transplantation
saphenous vein graft
Stents
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Summary:A lower lymphocyte count and a high monocyte count give important clues about the prognosis of various cardiovascular diseases. We hypothesized that lymphocyte-to-monocyte ratio (LMR) was associated with the saphenous vein graft disease (SVGD) in patients with coronary artery bypass graft (CABG). A total of 218 patients with previous history of CABG surgery, who underwent coronary angiography due to stable angina symptoms, were investigated, retrospectively. LMR levels were significantly lower in the SVGD group. Multiple logistic regression analyses showed that LMR levels were independent predictors of SVGD (OR: 0.648; 95% CI: 0.469-0.894; p = 0.008). Our results suggested that LMR levels may provide useful information for the relevant risk evaluation of SVGD in CABG patients.
ISSN:1752-0363
1752-0371
DOI:10.2217/bmm-2017-0079