Clinical characteristics of Parkinson's disease among Jewish Ethnic groups in Israel

Yemenite Jews in Israel are a distinctive ethnic division of the Jewish diaspora. Clinical findings, disease course and genetic tests for the LRRK2 6055G > A (G2019S) mutation were compared between Ashkenazi and Yemenite Israeli patients with Parkinson’s disease (PD). Age of onset was significant...

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Bibliographic Details
Published in:Journal of Neural Transmission 2008-09, Vol.115 (9), p.1279-1284
Main Authors: Djaldetti, Meir, Hassin-Baer, Sharon, Vidne, Bernardo A., Yust-Katz, Shlomit, Treves, Therese A, Melamed, Eldad
Format: Article
Language:English
Subjects:
Age of Onset
Aged
Disease Progression
DNA Mutational Analysis
Environment
Female
Gene Frequency - genetics
Genetic Predisposition to Disease - ethnology
Genetic Predisposition to Disease - genetics
Genetic Testing
Genotype
Humans
Inheritance Patterns - genetics
Israel - epidemiology
Jews - ethnology
Jews - genetics
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Male
Medicine
Medicine & Public Health
Middle Aged
Mutation - genetics
Neurology
Neurosciences
Parkinson Disease - ethnology
Parkinson Disease - genetics
Parkinson Disease - physiopathology
Parkinson's disease
Parkinson's Disease and Allied Conditions - Original Article
Protein-Serine-Threonine Kinases - genetics
Psychiatry
Severity of Illness Index
Yemen - ethnology
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Summary:Yemenite Jews in Israel are a distinctive ethnic division of the Jewish diaspora. Clinical findings, disease course and genetic tests for the LRRK2 6055G > A (G2019S) mutation were compared between Ashkenazi and Yemenite Israeli patients with Parkinson’s disease (PD). Age of onset was significantly younger in the Yemenites ( P  
ISSN:0300-9564
1435-1463
DOI:10.1007/s00702-008-0074-z