Time to Occurrence Based on Risk Stratification of Hospital-Acquired Venous Thromboembolism: A Retrospective Observational Cohort Study

Background: In-hospital venous thromboembolism (VTE) causes significant morbidity and mortality in hospitalized patients. The objective of our study is to determine the time to in-hospital VTE based on baseline risk stratification. Methods: All adult patients admitted to a 900-bed academic tertiary...

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Bibliographic Details
Published in:Journal of pharmacy practice 2018-12, Vol.31 (6), p.651-657
Main Authors: Tatara, Alexandra W., Ruegger, Melanie, Adeola, Mobolaji, Putney, David
Format: Article
Language:English
Subjects:
Adult
Aged
Cohort Studies
Female
Hospitalization
Humans
Iatrogenic Disease - epidemiology
Male
Middle Aged
Retrospective Studies
Risk Assessment
Tertiary Care Centers
Time Factors
Venous Thromboembolism - epidemiology
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Summary:Background: In-hospital venous thromboembolism (VTE) causes significant morbidity and mortality in hospitalized patients. The objective of our study is to determine the time to in-hospital VTE based on baseline risk stratification. Methods: All adult patients admitted to a 900-bed academic tertiary referral hospital who developed a VTE during hospital admission from September 1, 2011, to June 30, 2015, were retrospectively analyzed. Patients were excluded if they were younger than 18 years or if the VTE was present on admission. Results: The cohort included 400 patients, 224 (56%) males, median age 66 years. The median time to VTE was 8 days. Significant differences in time to VTE existed between the risk groups. Conclusion: Time to VTE in a broad hospitalized patient population differs based on admission risk group. This finding highlights the importance of performing risk assessment upon admission and subsequently with clinical changes to assess increases in risk scores.
ISSN:0897-1900
1531-1937
DOI:10.1177/0897190017735423