An enzymatic method for the production of 6-oxohexanoic acid from 6-aminohexanoic acid by an enzyme oxidizing ω-amino compounds from Phialemonium sp. AIU 274

An enzymatic method for 6-oxohexanoic acid production was developed using 6-aminohexanoic acid and an ω-amino group-oxidizing enzyme (ω-AOX) from Phialemonium sp. AIU 274. 6-Oxohexanoic acid was produced from 6-aminohexanoic acid with 100% yield by incubation with 0.3 U of the ω-AOX and 20 U of cata...

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Bibliographic Details
Published in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2017-12, Vol.81 (12), p.2407-2410
Main Authors: Yamada, Miwa, Ooe, Mitsuaki, Sasaki, Tomoko, Miyazaki, Masao, Isobe, Kimiyasu
Format: Article
Language:English
Subjects:
6-aminohexanoic acid
6-oxohexanoic acid
Aminocaproic Acid - metabolism
Ascomycota - enzymology
Biocatalysis
Biotechnology - methods
Caproates - metabolism
Catalase - metabolism
Hydrogen-Ion Concentration
Oxidation-Reduction
Phialemonium sp
Temperature
ω-amino compound-oxidizing enzyme
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Summary:An enzymatic method for 6-oxohexanoic acid production was developed using 6-aminohexanoic acid and an ω-amino group-oxidizing enzyme (ω-AOX) from Phialemonium sp. AIU 274. 6-Oxohexanoic acid was produced from 6-aminohexanoic acid with 100% yield by incubation with 0.3 U of the ω-AOX and 20 U of catalase at 30 °C for 30 h in 0.1 M potassium phosphate buffer (pH 7.0).
ISSN:0916-8451
1347-6947
DOI:10.1080/09168451.2017.1383848