Prevalence and biochemical risk factors of diabetic peripheral neuropathy with or without neuropathic pain in Taiwanese adults with type 2 diabetes mellitus

To investigate the prevalence and risk factors for diabetic peripheral neuropathy with or without neuropathic pain in Taiwanese. A cross-sectional, hospital-based observational study was conducted. We enrolled 2837 adults with type 2 diabetes mellitus. Diabetic peripheral neuropathy with or without...

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Bibliographic Details
Published in:Diabetes & metabolic syndrome clinical research & reviews 2018-04, Vol.12 (2), p.111-116
Main Authors: Pai, Yen-wei, Lin, Ching-Heng, Lee, I-Te, Chang, Ming-Hong
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biomarkers - blood
Cholesterol, HDL - blood
Cohort Studies
Cross-Sectional Studies
Diabetes mellitus
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - diagnosis
Diabetes Mellitus, Type 2 - epidemiology
Diabetic Neuropathies - blood
Diabetic Neuropathies - diagnosis
Diabetic Neuropathies - epidemiology
Diabetic peripheral neuropathy
Female
Glycated Hemoglobin A - metabolism
Humans
Male
Middle Aged
Neuralgia - blood
Neuralgia - diagnosis
Neuralgia - epidemiology
Neuropathic pain
Prevalence
Risk factor
Risk Factors
Taiwan - epidemiology
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Summary:To investigate the prevalence and risk factors for diabetic peripheral neuropathy with or without neuropathic pain in Taiwanese. A cross-sectional, hospital-based observational study was conducted. We enrolled 2837 adults with type 2 diabetes mellitus. Diabetic peripheral neuropathy with or without pain were diagnosed using 2 validated screening tools, namely the Michigan Neuropathy Screening Instrument and Douleur Neuropathique 4 questionnaire. In our sample, 2233 participants had no neuropathy, 476 had diabetic peripheral neuropathy without pain, and 128 had diabetic peripheral neuropathy with neuropathic pain, representing an overall diabetic peripheral neuropathy prevalence of 21.3%, and the prevalence of neuropathic pain in diabetic peripheral neuropathy was 21.2%. Multivariate analysis revealed that older age (P
ISSN:1871-4021
1878-0334
DOI:10.1016/j.dsx.2017.09.013