Relationship between chronic kidney disease without diabetes mellitus and components of frailty in community‐dwelling Japanese older adults

Aim To evaluate the relationship between kidney function without diabetes and components of the frailty phenotype in community‐dwelling Japanese older adults. Methods Participants were 8343 residents who completed baseline assessments, classified into four categories according to eGFR. Frailty statu...

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Bibliographic Details
Published in:Geriatrics & gerontology international 2018-02, Vol.18 (2), p.286-292
Main Authors: Lee, Sungchul, Lee, Sangyoon, Bae, Seongryu, Harada, Kazuhiro, Jung, Songee, Imaoka, Masakazu, Makizako, Hyuma, Doi, Takehiko, Shimada, Hiroyuki
Format: Article
Language:English
Subjects:
Aged
chronic kidney disease
Diabetes
Diabetes Mellitus - epidemiology
estimated glomerular filtration rate
frail
Frailty
Frailty - epidemiology
Humans
Independent Living
Japan - epidemiology
Kidney diseases
older adults
Older people
Renal Insufficiency, Chronic - epidemiology
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Summary:Aim To evaluate the relationship between kidney function without diabetes and components of the frailty phenotype in community‐dwelling Japanese older adults. Methods Participants were 8343 residents who completed baseline assessments, classified into four categories according to eGFR. Frailty status was defined using five criteria: (i) slow gait speed; (ii) muscle weakness; (iii) low physical activity; (iv) exhaustion; and (v) unintentional weight loss. Results After multivariate adjustment, participants with the lowest kidney function were at higher risk of frailty (OR 1.57, 95% CI 1.02–3.50) than those with normal kidney function. In addition, after adjustment for multiple confounders, estimated glomerular filtration rate
ISSN:1444-1586
1447-0594
DOI:10.1111/ggi.13180