Effects of vitamin D deficiency on left atrial function as evaluated by 2D speckle‐tracking echocardiography

• Published in: Journal of clinical ultrasound 2018-06, Vol.46 (5), p.334-340
• Main Authors: Akhavan‐Khaleghi, Niloofar, Hosseinsabet, Ali, Mohseni‐Badalabadi, Reza
• Format: Article
• Language: English
• Subjects: 2D speckle‐tracking echocardiography; Angiography; Cardiovascular disease; Cardiovascular system; Coronary artery; Coronary artery disease; Echocardiography; Heart diseases; left atrium; Patients; Strain rate; Tracking; Ultrasonic imaging; Vitamin D; Vitamin deficiency
• ISSN: 0091-2751; 1097-0096
• DOI: 10.1002/jcu.22548

Purpose Vitamin D deficiency is prevalent the world over, and some of its effects on the cardiovascular system have been previously demonstrated. We evaluated left atrial (LA) function via 2D speckle‐tracking echocardiography (2DSTE) in subjects with and without vitamin D deficiency. Methods Ninety‐seven consecutive patients without significant coronary artery disease on selective coronary angiography were incorporated in our study and divided according to their serum level of vitamin D into 2 groups: with and without vitamin D deficiency. Results The early diastolic strain rate, as a marker of LA conduit function, was increased in patients with vitamin D deficiency (P = .008) and after adjustment for age (P = .046). However, after adjustment for all the confounding factors, vitamin D deficiency showed only a trend to be the independent determinant of LA early diastolic longitudinal strain rate (SRE, P = .065). Conclusions Our findings indicated that LA function, as evaluated by 2DSTE, was not different between subjects with and without vitamin D deficiency after adjustment for the confounding factors.