Prognostic significance of the preoperative neutrophil-to-lymphocyte ratio for complete resection of thymoma

Purpose The preoperative peripheral neutrophil-to-lymphocyte ratio (NLR) is associated with a poor prognosis for various cancers. We evaluated the prognostic role of the preoperative NLR in patients with thymoma. Methods We reviewed the medical records of 254 patients who underwent resection of thym...

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Bibliographic Details
Published in:Surgery today (Tokyo, Japan) Japan), 2018-04, Vol.48 (4), p.422-430
Main Authors: Yanagiya, Masahiro, Nitadori, Jun-ichi, Nagayama, Kazuhiro, Anraku, Masaki, Sato, Masaaki, Nakajima, Jun
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Biomarkers, Tumor - blood
Female
Humans
Leukocyte Count
Lymphocytes
Male
Medicine
Medicine & Public Health
Middle Aged
Neutrophils
Original Article
Preoperative Period
Prognosis
Surgery
Surgical Oncology
Survival Rate
Thymoma - blood
Thymoma - diagnosis
Thymoma - mortality
Thymoma - surgery
Thymus Neoplasms - blood
Thymus Neoplasms - diagnosis
Thymus Neoplasms - mortality
Thymus Neoplasms - surgery
Young Adult
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Summary:Purpose The preoperative peripheral neutrophil-to-lymphocyte ratio (NLR) is associated with a poor prognosis for various cancers. We evaluated the prognostic role of the preoperative NLR in patients with thymoma. Methods We reviewed the medical records of 254 patients who underwent resection of thymic epithelial tumors at our institution. Patients were excluded if they had received steroid therapy, neoadjuvant therapy, or incomplete resection, or if they had thymic carcinoma or Good’s syndrome, recurrence of thymoma, or missing data. The NLR was measured preoperatively, and outcomes of patients with a low (
ISSN:0941-1291
1436-2813
DOI:10.1007/s00595-017-1602-y