Detection of lung carcinoma with predominant ground-glass opacity on CT using temporal subtraction method

Purpose To evaluate the usefulness of the CT temporal subtraction (TS) method for the detection of the lung cancer with predominant ground-glass opacity (LC-pGGO). Materials and methods Twenty-five pairs of CT and their TS images in patients with LC-pGGO (31 lesions) and 25 pairs of those in patient...

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Bibliographic Details
Published in:European radiology 2018-04, Vol.28 (4), p.1594-1599
Main Authors: Terasawa, Takashi, Aoki, Takatoshi, Murakami, Seiichi, Kim, Hyoungseop, Fujii, Masami, Kobayashi, Michiko, Chihara, Chihiro, Hayashida, Yoshiko, Korogi, Yukunori
Format: Article
Language:English
Subjects:
Adult
Aged
Cancer
Computed tomography
Computer Applications
Diagnostic Radiology
Female
Humans
Imaging
Internal Medicine
Interventional Radiology
Lesions
Lung - diagnostic imaging
Lung cancer
Lung carcinoma
Lung Neoplasms - diagnostic imaging
Male
Medicine
Medicine & Public Health
Middle Aged
Neuroradiology
Nodules
Opacity
Patients
Radiographic Image Interpretation, Computer-Assisted - methods
Radiology
Reproducibility of Results
Sensitivity and Specificity
Statistical analysis
Statistical significance
Subtraction
Subtraction Technique
Tomography, X-Ray Computed - methods
Ultrasound
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Summary:Purpose To evaluate the usefulness of the CT temporal subtraction (TS) method for the detection of the lung cancer with predominant ground-glass opacity (LC-pGGO). Materials and methods Twenty-five pairs of CT and their TS images in patients with LC-pGGO (31 lesions) and 25 pairs of those in patients without nodules were used for an observer performance study. Eight radiologists participated and the statistical significance of differences with and without the CT-TS was assessed by JAFROC analysis. Results The average figure-of-merit (FOM) values for all radiologists increased to a statistically significant degree, from 0.861 without CT-TS to 0.912 with CT-TS ( p < .001). The average sensitivity for detecting the actionable lesions improved from 73.4 % to 85.9 % using CT-TS. The reading time with CT-TS was not significantly different from that without. Conclusion The use of CT-TS improves the observer performance for the detection of LC-pGGO. Key Points • CT temporal subtraction can improve the detection accuracy of lung cancer . • Reading time with temporal subtraction is not different from that without . • CT temporal subtraction improves observer performance for ground-glass/subsolid nodule detection .
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-017-5085-4