Improved synthesis of 2-amino-1,2,4-triazolo[1,5-a]pyrimidines

An improved procedure is suggested for preparing 2-amino-1,2,4-triazolo[1,5-a]pyrimidines from 3,5-diamino-1,2,4-triazole and unsaturated aromatic ketones, with acetyl protection of the amino group in the step of oxidation of 2-amino-4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidines.

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Bibliographic Details
Published in:Russian journal of applied chemistry 2006-07, Vol.79 (7), p.1134-1137
Main Authors: Chernyshev, V. M., Sokolov, A. N., Taranushich, V. A.
Format: Article
Language:English
Subjects:
Ketones
Oxidation
Pyrimidines
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Summary:An improved procedure is suggested for preparing 2-amino-1,2,4-triazolo[1,5-a]pyrimidines from 3,5-diamino-1,2,4-triazole and unsaturated aromatic ketones, with acetyl protection of the amino group in the step of oxidation of 2-amino-4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidines.
ISSN:1070-4272
1608-3296
DOI:10.1134/S1070427206070172