The impact of neurally adjusted ventilatory assist mode on respiratory severity score and energy expenditure in infants: a randomized crossover trial

Objective: Examine respiratory severity scores (RSS) (mean airway pressure × fraction of inspired oxygen) and resting energy expenditure (REE) on neurally adjusted ventilatory assist (NAVA) compared with synchronized intermittent mandatory ventilation with pressure controlled and supported breath (S...

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Bibliographic Details
Published in:Journal of perinatology 2018-01, Vol.38 (1), p.59-63
Main Authors: Rosterman, J L, Pallotto, E K, Truog, W E, Escobar, H, Meinert, K A, Holmes, A, Dai, H, Manimtim, W M
Format: Article
Language:English
Subjects:
692/700/139
Breathing
Comparative analysis
Energy expenditure
Health aspects
Infants
Mechanical ventilation
Medical schools
Medicine
Medicine & Public Health
Neonatal intensive care
Neonates
Newborn infants
original-article
Oxygen
Oxygen requirement
Pediatric Surgery
Pediatrics
Pressure
Randomization
Respiration
Respiratory therapy
Respiratory tract
Respiratory tract infections
Ventilation
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Summary:Objective: Examine respiratory severity scores (RSS) (mean airway pressure × fraction of inspired oxygen) and resting energy expenditure (REE) on neurally adjusted ventilatory assist (NAVA) compared with synchronized intermittent mandatory ventilation with pressure controlled and supported breath (SIMV (PC)PS). Study Design: A randomized, crossover trial in a level IV neonatal intensive care unit. Twenty-four patients were ventilated with NAVA or SIMV (PC) PS for 12 h and then crossed over to the alternative mode for 12 h. The primary outcome (RSS) and additional secondary respiratory outcomes were analyzed. Results: RSS and measured REE were not different between modes. On NAVA, peak inspiratory pressures were lower (17.8 vs 19.9 cmH 2 O ( P
ISSN:0743-8346
1476-5543
DOI:10.1038/jp.2017.154