Functional Information in Coronary Artery Disease: The Case of Computed Tomography Myocardial Perfusion

Purpose of Review To review methodological and logistical aspects of CT myocardial perfusion, current clinical evidence and possible future directions, with specific focus on use in patients with coronary artery disease (CAD). Recent Findings CT myocardial perfusion imaging may be performed as an ad...

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Bibliographic Details
Published in:Current cardiology reports 2017-10, Vol.19 (12), p.126-126, Article 126
Main Authors: Kofoed, Klaus F., Sørgaard, Mathias H., Linde, Jesper J.
Format: Article
Language:English
Subjects:
Cardiac PET
Cardiology
Medicine
Medicine & Public Health
MRI
MRI (F Pugliese and SE Petersen
Section Editor
Topical Collection on Cardiac PET
Citations: Items that this one cites
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Summary:Purpose of Review To review methodological and logistical aspects of CT myocardial perfusion, current clinical evidence and possible future directions, with specific focus on use in patients with coronary artery disease (CAD). Recent Findings CT myocardial perfusion imaging may be performed as an add-on to standard coronary CT angiography (CCTA), to identify regions of myocardial hypoperfusion, at rest and during adenosine stress. The principle of measurement is well-validated in animal experimental models, and CT myocardial perfusion imaging has a high degree of concordance with already clinically available perfusion imaging methods. Combining CCTA and CT myocardial perfusion imaging increases the diagnostic accuracy to identify patients with CAD associated with ischemia. Summary In patients suspected of CAD, CCTA frequently detects coronary atherosclerotic lesions, in which revascularization could be clinically beneficial. CT myocardial perfusion imaging may be helpful to identify coronary lesions associated with myocardial ischemia, and thus potentially suitable for coronary intervention.
ISSN:1523-3782
1534-3170
DOI:10.1007/s11886-017-0937-8