A Noninvasive Rhizopus Infection With a Bladder Fungal Ball in a Patient With Poorly Controlled Diabetes Mellitus

Abstract Here we present the first reported case of a noninvasive Rhizopus fungal ball confined to the bladder of a patient with poorly controlled diabetes and right flank pain. The patient developed bilateral hydronephrosis after several hospital admissions for urinary tract infections with multipl...

Full description

Saved in:
Bibliographic Details
Published in:Laboratory medicine 2018-02, Vol.49 (1), p.75-79
Main Authors: Barnes, Aaron M T, Crespo-Diaz, Ruben J, Cohenour, Justin, Kirsch, Jonathan D, Arbefeville, Sophie, Ferrieri, Patricia
Format: Article
Language:English
Subjects:
Amphotericin B - therapeutic use
Antifungal agents
Antifungal Agents - therapeutic use
Bladder
Cystoscopy
Diabetes
Diabetes Complications
Fungal infections
Humans
Male
Middle Aged
Mucormycosis
Rhizopus - isolation & purification
Urinary Bladder - diagnostic imaging
Urinary Bladder - microbiology
Urinary Bladder - pathology
Urinary Bladder Diseases
Urinary tract diseases
Urinary tract infections
Urogenital system
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Here we present the first reported case of a noninvasive Rhizopus fungal ball confined to the bladder of a patient with poorly controlled diabetes and right flank pain. The patient developed bilateral hydronephrosis after several hospital admissions for urinary tract infections with multiple failed courses of antibiotics. During cystoscopy to replace a ureteral stent, he was found to harbor a fungal ball in the bladder that was removed and grew Rhizopus in culture. Patient received treatment with amphotericin B and transitioned to long-term posaconazole therapy. This case highlights the importance of considering fungal agents in urinary tract infections, especially in persistent or refractory cases, and the role of the clinical microbiology laboratory in correct identification of the infectious source.
ISSN:0007-5027
1943-7730
DOI:10.1093/labmed/lmx060