Upper airway stimulation therapy and prior airway surgery for obstructive sleep apnea

• Published in: The Laryngoscope 2018-06, Vol.128 (6), p.1486-1489
• Main Authors: Mahmoud, Ahmad F., Thaler, Erica R.
• Format: Article
• Language: English
• Subjects: Adult; Aged; Apnea‐Hypopnea Index; Electric Stimulation Therapy - methods; Epworth Sleepiness Scale; Female; Humans; Hypoglossal Nerve - surgery; Hypoglossal nerve stimulation; Male; Middle Aged; nadir oxyhemoglobin saturation; obstructive sleep apnea; OSA; Polysomnography; Retrospective Studies; Severity of Illness Index; Sleep apnea; Sleep Apnea, Obstructive - surgery; Surgery; Treatment Outcome; upper airway stimulation
• ISSN: 0023-852X; 1531-4995
• DOI: 10.1002/lary.26956

Objective To determine if patients with prior airway surgery for obstructive sleep apnea (OSA) had increased benefit following implantation with hypoglossal nerve stimulator. Study Design Retrospective chart review at a single institution tertiary academic care center. Methods Following implantation with hypoglossal nerve stimulator device, the outcomes of patients who underwent prior airway surgery for OSA were compared with those who did not. Primary outcome measures included apnea‐hypopnea index (AHI) and nadir oxyhemoglobin saturation (NOS) as measured by polysomnography. Secondary outcome measures included Epworth Sleepiness Scale. Results Forty‐seven patients underwent implantation with hypoglossal nerve stimulator. Of these, 30 patients had undergone prior airway surgery for OSA, whereas 16 did not. Mean preoperative AHI and NOS were 39.3 ± 2.8 and 78% ± 1.8% for all patients, 39.4 ± 3.7 and 79% ± 14% for patients with prior airway surgery, and 39.1 ± 4.0 and 77% ± 2.6% for patients without prior surgery. Mean postoperative AHI and NOS were 3.9 ± 1.2 and 91% ± 0.4% for all patients, 4.2 ± 1.7 and 91% ± 0.5% for patients with prior surgery, and 3.4 ± 1.5 and 93% ± 0.6% for patients without prior surgery (P = 0.756 and 0.053, respectively). Conclusion Overall, patients had significant improvement following implantation with hypoglossal nerve stimulator. Prior airway surgery had no statistically significant effect on postoperative AHI or NOS. Level of Evidence 4. Laryngoscope, 128:1486–1489, 2018