In Vitro Antimicrobial Activity and Downregulation of Virulence Gene Expression on Helicobacter pylori by Reuterin

Helicobacter pylori is an infectious agent commonly associated with gastrointestinal diseases. The use of probiotics to treat this infection has been documented, however, their potential antimicrobial metabolites have not yet been investigated. In the present study, the effect of reuterin produced b...

Full description

Saved in:
Bibliographic Details
Published in:Probiotics and antimicrobial proteins 2018-06, Vol.10 (2), p.168-175
Main Authors: Urrutia-Baca, Víctor Hugo, Escamilla-García, Erandi, de la Garza-Ramos, Myriam Angélica, Tamez-Guerra, Patricia, Gomez-Flores, Ricardo, Urbina-Ríos, Cynthia Sofía
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - metabolism
Anti-Bacterial Agents - pharmacology
Applied Microbiology
Bacterial Proteins - genetics
Bacterial Proteins - metabolism
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Glyceraldehyde - analogs & derivatives
Glyceraldehyde - metabolism
Glyceraldehyde - pharmacology
Helicobacter Infections - microbiology
Helicobacter pylori - drug effects
Helicobacter pylori - genetics
Helicobacter pylori - growth & development
Helicobacter pylori - metabolism
Humans
Lactobacillus reuteri - metabolism
Microbial Sensitivity Tests
Microbiology
Nutrition
Propane - metabolism
Propane - pharmacology
Protein Science
Virulence Factors - genetics
Virulence Factors - metabolism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Helicobacter pylori is an infectious agent commonly associated with gastrointestinal diseases. The use of probiotics to treat this infection has been documented, however, their potential antimicrobial metabolites have not yet been investigated. In the present study, the effect of reuterin produced by Lactobacillus reuteri on H. pylori growth and virulence gene expression was evaluated. It was observed that reuterin caused significant ( P  
ISSN:1867-1306
1867-1314
DOI:10.1007/s12602-017-9342-2