Gastric accommodation in healthy subjects studied by ultrasound, manometry, and impedancemetry

Background Gastric accommodation to a meal may be important in the pathogenesis of upper gastrointestinal disorders, but has been difficult to investigate in a minimally invasive fashion. Methods We studied gastric and lower esophageal physiology during food intake, combining transabdominal ultrasou...

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Bibliographic Details
Published in:Neurogastroenterology and motility 2018-04, Vol.30 (4), p.e13249-n/a
Main Authors: Storlid, E. L., Hausken, T., Lied, G. A., Gilja, O. H., Hatlebakk, J. G.
Format: Article
Language:English
Subjects:
Esophagus
Fluid intake
Food intake
gastric accommodation
gastric motility
gastroesophageal reflux
Gastrointestinal diseases
impedancemetry
manometry
Pressure
Stomach
Ultrasonic imaging
ultrasonography
Ultrasound
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Summary:Background Gastric accommodation to a meal may be important in the pathogenesis of upper gastrointestinal disorders, but has been difficult to investigate in a minimally invasive fashion. Methods We studied gastric and lower esophageal physiology during food intake, combining transabdominal ultrasound, multichannel high‐resolution impedance‐manometry (HRIM) and a symptom questionnaire. A HRIM catheter was distally positioned at incisura angularis and 300 mL saline with 75 g glucose was ingested. Target variables were recorded for 30 min after fluid intake. Key Results Fifteen healthy subjects’ participated (11W/4M, median age 23.8 y) and all accepted the meal with few symptoms. At incisura angularis maximum change in pressure from pre‐intake values was −7.4 mmHg after 60 s (P 
ISSN:1350-1925
1365-2982
DOI:10.1111/nmo.13249