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Ventricular fibrillation by anaphylaxis following consumption of blue_skinned fish

CaseApproximately 4_h after eating mackerel sushi, a 65_year_old man developed generalized itchiness and redness, after which he became unresponsive. He went into a state of ventricular fibrillation but after he was defibrillated twice, his heartbeat returned. The electrocardiogram obtained immediat...

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Published in:Acute medicine & surgery 2016, Vol.3 (2), p.159-162
Main Authors: Otsubo, Saori, Nishiyama, Takashi, Okada, Naoki, Ando, Yukihiro, Yamada, Katsumi, Maeda, Yuji, Nishimura, Yusuke
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container_issue 2
container_start_page 159
container_title Acute medicine & surgery
container_volume 3
creator Otsubo, Saori
Nishiyama, Takashi
Okada, Naoki
Ando, Yukihiro
Yamada, Katsumi
Maeda, Yuji
Nishimura, Yusuke
description CaseApproximately 4_h after eating mackerel sushi, a 65_year_old man developed generalized itchiness and redness, after which he became unresponsive. He went into a state of ventricular fibrillation but after he was defibrillated twice, his heartbeat returned. The electrocardiogram obtained immediately after hospitalization showed some ST_segment depression, but a subsequent electrocardiogram showed improvement. Coronary CT showed no obvious stenosis or plaque in the coronary artery. OutcomeResults of an IgE_RAST test confirmed that the level of allergen_specific IgE for mackerel measured
doi_str_mv 10.1002/ams2.144
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He went into a state of ventricular fibrillation but after he was defibrillated twice, his heartbeat returned. The electrocardiogram obtained immediately after hospitalization showed some ST_segment depression, but a subsequent electrocardiogram showed improvement. Coronary CT showed no obvious stenosis or plaque in the coronary artery. OutcomeResults of an IgE_RAST test confirmed that the level of allergen_specific IgE for mackerel measured &lt;0.10_UA/mL, while the level for anisakis was 1.91_UA/mL. ConclusionsAs for the mechanism leading to cardiac arrest, it is thought that the histamines and leukotrienes released from cardiac mast cells caused a coronary artery spasm (Kounis syndrome). 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He went into a state of ventricular fibrillation but after he was defibrillated twice, his heartbeat returned. The electrocardiogram obtained immediately after hospitalization showed some ST_segment depression, but a subsequent electrocardiogram showed improvement. Coronary CT showed no obvious stenosis or plaque in the coronary artery. OutcomeResults of an IgE_RAST test confirmed that the level of allergen_specific IgE for mackerel measured &lt;0.10_UA/mL, while the level for anisakis was 1.91_UA/mL. ConclusionsAs for the mechanism leading to cardiac arrest, it is thought that the histamines and leukotrienes released from cardiac mast cells caused a coronary artery spasm (Kounis syndrome). 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He went into a state of ventricular fibrillation but after he was defibrillated twice, his heartbeat returned. The electrocardiogram obtained immediately after hospitalization showed some ST_segment depression, but a subsequent electrocardiogram showed improvement. Coronary CT showed no obvious stenosis or plaque in the coronary artery. OutcomeResults of an IgE_RAST test confirmed that the level of allergen_specific IgE for mackerel measured &lt;0.10_UA/mL, while the level for anisakis was 1.91_UA/mL. ConclusionsAs for the mechanism leading to cardiac arrest, it is thought that the histamines and leukotrienes released from cardiac mast cells caused a coronary artery spasm (Kounis syndrome). This anaphylactic shock is considered to be a result of anisakis allergy, but in general cases of anaphylaxis resulting from consumption of blue_skinned fish.</abstract><doi>10.1002/ams2.144</doi></addata></record>
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title Ventricular fibrillation by anaphylaxis following consumption of blue_skinned fish
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