Expression of the 1A and 2A serotonin receptor genes in the brain of rats adapted to warm and cold

1. The effect of long-term thermal adaptation on expression of 5-HT 1A and 5-HT 2A receptor genes was studied by quantitative RT-PCR in brain regions of rats adapted for 5 weeks to warm (+20 to +22 °C) or cold (+4 to +6 °C). 2. No differences were found in the 5-HT 1A receptor mRNA levels in the rat...

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Bibliographic Details
Published in:Journal of thermal biology 2007-05, Vol.32 (4), p.188-192
Main Authors: Voronova, Irina P., Kulikov, Alexandr V., Popova, Nina K., Kozyreva, Tamara V.
Format: Article
Language:English
Subjects:
5-HT 1A
5-HT 2A receptors
Long-term thermal adaptation
mRNA
Rat
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Summary:1. The effect of long-term thermal adaptation on expression of 5-HT 1A and 5-HT 2A receptor genes was studied by quantitative RT-PCR in brain regions of rats adapted for 5 weeks to warm (+20 to +22 °C) or cold (+4 to +6 °C). 2. No differences were found in the 5-HT 1A receptor mRNA levels in the rats of two groups. 3. The 5-HT 2A receptor mRNA levels in cold-adapted rats in comparison to warm-adapted rats increased in hypothalamus and decreased in frontal cortex, but were unaltered in hippocampus.
ISSN:0306-4565
1879-0992
DOI:10.1016/j.jtherbio.2007.01.001