Validation of KDRI/KDPI for the selection of expanded criteria kidney donors

• Published in: Nefrología 2018-05, Vol.38 (3), p.297-303
• Main Authors: Del Moral Martín, Raimundo M García, Retamero Díaz, Juan Antonio, Cava Molina, Mercedes, Cobacho Tornel, Belen M, Bravo Soto, Juan, Osuna Ortega, Antonio, O'Valle Ravassa, Francisco
• Format: Article
• Language: eng ; spa
• ISSN: 2013-2514
• DOI: 10.1016/j.nefro.2017.08.006

INTRODUCTIONKDRI / KDPI are tools use in kidney donor evaluation. It has been proposed as a substitute of, or complementary to preimplantation renal biopsy. These scores has not been validated in Spain. OBJECTIVE1) To investigate the concordance between KDPI and histological scores (preimplantation renal biopsy) and 2) To assess the relationship between KDRI, KDPI and histological score on graft survival in the expanded criteria donors group. METHODOLOGYRetrospective cohort study from 1 January 1998 until 31 December 2010. RESULTSDuring the study 120 donors were recruited, that resulted in 220 preimplantation renal biopsies. 144 (65%) grafts were considered suitable for kidney transplantation. 76 (34.5%) were discarded. Median follow up has been 6.4 years (sd 3.9). Median age 63.1 years (sd 8.2), males (145; 65.9%), non-diabetic (191; 86.8%) and without another cardiovascular risk factors (173; 78.6%). 153 (69.5%) donors died of cerebrovascular disease. There were significant differences in KDRI/KDPI score in both groups 1.56/89 (sd 0.22) vs 1.66/93 (sd 0.15), p