Oxidative stress biomarkers of exposure in the blood of cichlid species from a metal-contaminated river

The oxidative stress biomarkers of exposure, such as reduced glutathione (GSH), activity of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) and the levels of lipid peroxidation (LPO), were measured in the blood of three cichlid fish ( Oreochromis niloticus, Tilapia rendal...

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Bibliographic Details
Published in:Ecotoxicology and environmental safety 2008-09, Vol.71 (1), p.86-93
Main Authors: Ruas, Clarissa Bonafé Gaspar, Carvalho, Cleoni dos Santos, de Araújo, Heloísa Sobreiro Selistre, Espíndola, Evaldo Luiz Gaeta, Fernandes, Marisa Narciso
Format: Article
Language:English
Subjects:
Animals
Antioxidant enzymes
Aquaporin 2
Biomarkers - blood
Blood
Brazil
Catalase - blood
Cichlidae
Cichlids
Cichlids - blood
Erythrocytes
Fish
Geophagus brasiliensis
Glutathione Peroxidase - blood
Hemoglobins
Lipid Peroxidation
Metals
Metals - toxicity
Oreochromis niloticus
Oxidative stress
Oxidative Stress - physiology
Pollution
Rivers - chemistry
Seasons
Superoxide Dismutase - blood
Tilapia rendalli
Water Pollutants, Chemical - toxicity
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Summary:The oxidative stress biomarkers of exposure, such as reduced glutathione (GSH), activity of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) and the levels of lipid peroxidation (LPO), were measured in the blood of three cichlid fish ( Oreochromis niloticus, Tilapia rendalli, and Geophagus brasiliensis) taken during two seasons from two sites, unpolluted and polluted by industrial effluents, to evaluate the effectiveness of these biomarkers in assessing the impact of water contamination. The LPO levels in the blood were higher in fish from the metal-contaminated site and the chronic exposure led to significant changes in GPx, CAT, and SOD activities in all three cichlid species. The considerable variation of responses in these cichlids to water contamination evidenced differences in sensitivity to the metal contamination and/or in the potential to respond to it highlighting the importance of using a set of related biomarkers to assess the impact of water contamination.
ISSN:0147-6513
1090-2414
DOI:10.1016/j.ecoenv.2007.08.018