Timing of regular egg intake for prevention of egg allergy

After delivery, infants have to face massive external antigens. [...]the immune system of the infant needs to balance 2 different jobs: immunotolerance to massive safe external antigens and prevention of infection. Infants live in a relatively safe environment with low level of pathogens due to the...

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2018-01, Vol.141 (1), p.459-460
Main Authors: Jiang, Wen-Hui, Deng, Li, Ye, Qing-Jian, Cai, Jia-Rong, Cai, Xiu-Rong, Li, Xing
Format: Article
Language:English
Subjects:
Allergies
Antigens
Asthma
Babies
Clinical trials
Immune system
Prevention
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Summary:After delivery, infants have to face massive external antigens. [...]the immune system of the infant needs to balance 2 different jobs: immunotolerance to massive safe external antigens and prevention of infection. Infants live in a relatively safe environment with low level of pathogens due to the protection of parents. [...]the major job of infant immune system is to induce immunotolerance to external antigens. Notably, these cells only exist shortly after birth, which indicated the key window for immunotolerance induction, first weeks after birth. [...]to prevent egg-related allergic disease, the regular egg intake shall be started shortly after birth by being added to milk.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2017.09.017