Experience with ceftaroline for treatment of methicillin-resistant Staphylococcus aureus pneumonia in a community hospital

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is an organism causing significant mortality and morbidity with nosocomial infections. Ceftaroline is a new cephalosporin antibiotic that has activity against MRSA. In the USA, this antibiotic has not been approved for use in pneumonia c...

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Bibliographic Details
Published in:Journal of community hospital internal medicine perspectives 2017-01, Vol.7 (5), p.300-302
Main Authors: Karki, Apurwa, Thurm, Craig, Cervellione, Kelly
Format: Article
Language:English
Subjects:
Antibiotics
ceftaroline
Cephalosporins
clinical success
Communities
Drug resistance
Endocarditis
Failure
Hospitals
Infectious diseases
Laboratories
Methicillin
Methicillin-resistant Staphylococcus aureus
Morbidity
Mortality
Nosocomial infection
Nosocomial infections
Patients
Pneumonia
retrospective study
Skin
Staphylococcus aureus
Staphylococcus infections
Success
Urban areas
Ventilators
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Summary:Background: Methicillin-resistant Staphylococcus aureus (MRSA) is an organism causing significant mortality and morbidity with nosocomial infections. Ceftaroline is a new cephalosporin antibiotic that has activity against MRSA. In the USA, this antibiotic has not been approved for use in pneumonia caused by MRSA. Objectives: To review the use of ceftaroline in MRSA pneumonia in a US hospital and evaluate its clinical success. Methods: A retrospective study was conducted in an urban community hospital assessing the use of ceftaroline for MRSA pneumonia. Results: The clinical success was comparable to the currently approved treatment for MRSA pneumonia. Conclusion: The results of our study showed a favorable result for the treatment of MRSA pneumonia. Well-designed studies need to be performed for further validation of these results.
ISSN:2000-9666
2000-9666
DOI:10.1080/20009666.2017.1374107