A new topical treatment of atopic dermatitis in pediatric patients based on Ficus carica L. (Fig): A randomized, placebo-controlled clinical trial

•Our randomized, placebo-controlled trial indicated the new treatment for children atopic dermatitis.•Application of aqueous extract of fig fruit (F.carica) can offer better treatment outcome rather than Hydrocortisone 1% in mild to moderate atopic dermatitis.•There have been no immediate side effec...

Full description

Saved in:
Bibliographic Details
Published in:Complementary therapies in medicine 2017-12, Vol.35, p.85-91
Main Authors: Abbasi, Shirin, Kamalinejad, Mohammad, Babaie, Delara, Shams, SeyedMohammad, Sadr, Zahra, Gheysari, Mehdi, Askari, Vahid Reza, Rakhshandeh, Hassan
Format: Article
Language:English
Subjects:
Administration, Topical
Adolescent
Atopic dermatitis
Child
Child, Preschool
Clinical trials
Corticosteroids
Dermatitis
Dermatitis, Atopic - complications
Dermatitis, Atopic - drug therapy
Double-Blind Method
Eczema
Evidence-based medicine
Female
Ficus
Ficus carica
Ficus carica L
Fruit
Fruits
Herbal agents
Humans
Hydrocortisone
Hydrocortisone - therapeutic use
Hydrocortisone 1.0
Infant
Male
Ointments
Pediatrics
Phytotherapy
Plant Preparations - administration & dosage
Plant Preparations - pharmacology
Plant Preparations - therapeutic use
Pruritus - drug therapy
Pruritus - etiology
Scoring atopic dermatitis (SCORAD)
Severity of Illness Index
Steroids
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:•Our randomized, placebo-controlled trial indicated the new treatment for children atopic dermatitis.•Application of aqueous extract of fig fruit (F.carica) can offer better treatment outcome rather than Hydrocortisone 1% in mild to moderate atopic dermatitis.•There have been no immediate side effects from its use every day for two weeks. Atopic dermatitis (AD) is a common, chronic, relapsing and inflammatory skin disease characterized by pruritus and xerosis (dry skin). Its prevalence is on the increase worldwide, particularly in children. As the pathogenesis of AD involves a complex interaction of genetic, environmental and immunological factors, its definitive treatment is difficult. This clinical trial was designed as equivalence study to investigate the effect of aqueous extract of edible dried fig fruit on the severity of AD as measured with scoring atopic dermatitis (SCORAD), in comparison with Hydrocortisone 1.0% as the routine treatment of AD and base cream as a placebo. Forty five children aged 4 months to 14 years with mild to moderate AD (SCORAD
ISSN:0965-2299
1873-6963
DOI:10.1016/j.ctim.2017.10.003