TNF- alpha , CXCL8, big ET-1 and hsCRP in Patients with Chronic Obstructive Pulmonary Disease

COPD (chronic obstructive pulmonary disease) is a chronic progressive inflammatory disease characterised by limitations in lung airflow that is not fully reversible. The concentrations and correlations of TNF- alpha , CXCL8, big ET-1 and hsCRP were investigated in healthy non-smokers, healthy smoker...

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Bibliographic Details
Published in:Biological cybernetics 1997-11, Vol.77 (5), p.211-217
Main Authors: Marevic, S, Petrik, J, Vrkic, N, Popovic-Grle, S, Zanic-Grubisic, T, Cepelak, I
Format: Article
Language:hrv ; eng
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Summary:COPD (chronic obstructive pulmonary disease) is a chronic progressive inflammatory disease characterised by limitations in lung airflow that is not fully reversible. The concentrations and correlations of TNF- alpha , CXCL8, big ET-1 and hsCRP were investigated in healthy non-smokers, healthy smokers and patients with COPD in order to study their possible role in the patho-physiology of COPD. The concentrations of TNF- alpha , CXCL8 and big ET-1 were not statistically different between the experimental groups. No significant differences for the measured analytes were found between smokers and the non-smokers in the control group. The Spearman coefficient of correlation between the concentrations of TNF- alpha and CXCL8 was r = 0.638 (p
ISSN:0340-1200