Early Elevated Troponin Levels After Ischemic Stroke Suggests a Cardioembolic Source

Elevated cardiac troponin is a marker of cardiac disease and has been recently shown to be associated with embolic stroke risk. We hypothesize that early elevated troponin levels in the acute stroke setting are more prevalent in patients with embolic stroke subtypes (cardioembolic and embolic stroke...

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Published in:Stroke (1970) 2018-01, Vol.49 (1), p.121-126
Main Authors: Yaghi, Shadi, Chang, Andrew D, Ricci, Brittany A, Jayaraman, Mahesh V, McTaggart, Ryan A, Hemendinger, Morgan, Narwal, Priya, Dakay, Katarina, Mac Grory, Brian, Cutting, Shawna M, Burton, Tina M, Song, Christopher, Mehanna, Emile, Siket, Matthew, Madsen, Tracy E, Reznik, Michael, Merkler, Alexander E, Lerario, Michael P, Kamel, Hooman, Elkind, Mitchell S V, Furie, Karen L
Format: Article
Language:English
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Summary:Elevated cardiac troponin is a marker of cardiac disease and has been recently shown to be associated with embolic stroke risk. We hypothesize that early elevated troponin levels in the acute stroke setting are more prevalent in patients with embolic stroke subtypes (cardioembolic and embolic stroke of unknown source) as opposed to noncardioembolic subtypes (large-vessel disease, small-vessel disease, and other). We abstracted data from our prospective ischemic stroke database and included all patients with ischemic stroke during an 18-month period. Per our laboratory, we defined positive troponin as ≥0.1 ng/mL and intermediate as ≥0.06 ng/mL and
ISSN:0039-2499
1524-4628
DOI:10.1161/STROKEAHA.117.019395