Short body length phenotype is compensated by the upregulation of nidogen family members in a deleterious nid1a mutation of zebrafish

To decode biological processes,interfering with gene functions is a widely used strategy.There are a number of ways to interfere with gene functions.For instance,small interfering RNAs（siRNAs）are used to induce mRNA degradation;morpholinos are used to block protein translation（Nasevicius and Ekker,2...

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Bibliographic Details
Published in:Journal of genetics and genomics 2017-11, Vol.44 (11), p.553-556
Main Authors: Zhu, Peipei, Ma, Zhipeng, Guo, Liwei, Zhang, Wei, Zhang, Qinghe, Zhao, Ting, Jiang, Kunpeng, Peng, Jinrong, Chen, Jun
Format: Article
Language:English
Subjects:
Animals
Body Size - genetics
Calcium-Binding Proteins - deficiency
Calcium-Binding Proteins - genetics
Membrane Glycoproteins - deficiency
Membrane Glycoproteins - genetics
Phenotype
Sequence Deletion
Up-Regulation
Zebrafish - anatomy & histology
Zebrafish - genetics
Zebrafish Proteins - deficiency
Zebrafish Proteins - genetics
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Summary:To decode biological processes,interfering with gene functions is a widely used strategy.There are a number of ways to interfere with gene functions.For instance,small interfering RNAs（siRNAs）are used to induce mRNA degradation;morpholinos are used to block protein translation（Nasevicius and Ekker,2000）;
ISSN:1673-8527
DOI:10.1016/j.jgg.2017.09.011