No improvement in long-term survival for epithelial ovarian cancer patients: A population-based study between 1989 and 2014 in the Netherlands

This study investigates changes in therapy and long-term survival for patients with epithelial ovarian cancer (EOC) in the Netherlands. All patients with EOC, including peritoneal and fallopian tube carcinoma, diagnosed in the Netherlands between 1989 and 2014 were selected from the Netherlands Canc...

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Bibliographic Details
Published in:European journal of cancer (1990) 2018-01, Vol.88, p.31-37
Main Authors: Timmermans, M., Sonke, G.S., Van de Vijver, K.K., van der Aa, M.A., Kruitwagen, R.F.P.M.
Format: Article
Language:English
Subjects:
Cancer
Chemotherapy
Disease control
Dissection
Epithelial ovarian cancer
Fallopian tube
Genital cancers
Lymph nodes
Migration
Ovarian cancer
Overall survival
Patients
Peritoneum
Population studies
Population-based studies
Regression analysis
Regression models
Studies
Surgery
Survival
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Summary:This study investigates changes in therapy and long-term survival for patients with epithelial ovarian cancer (EOC) in the Netherlands. All patients with EOC, including peritoneal and fallopian tube carcinoma, diagnosed in the Netherlands between 1989 and 2014 were selected from the Netherlands Cancer Registry. Changes in therapy were studied and related to overall survival (OS) using multivariable Cox regression models. A total of 32,540 patients were diagnosed with EOC of whom 22,047 (68%) had advanced stage disease. In early stage, lymph node dissection as part of surgical staging procedures increased over time from 4% in 1989–1993 to 62% in 2009–2014 (P 
ISSN:0959-8049
1879-0852
DOI:10.1016/j.ejca.2017.10.030