Synthesis of fused pyrimidines from amines and cyclic β-formylesters

A highly efficient method was successfully developed for the synthesis of fused pyrimidines via aminoheterocyclic dihydrofuranone intermediates obtained from 2-aminoheterocycles and cyclic β-formylesters by three different methods. [Display omitted]

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Bibliographic Details
Published in:Tetrahedron 2007-08, Vol.63 (34), p.8157-8163
Main Authors: Toche, Raghunath B., Ghotekar, Bhausaheb K., Kazi, Muddassar A., Kendre, Dhananjay B., Jachak, Madhukar N.
Format: Article
Language:English
Subjects:
Aminoheterocyclic dihydrofuranone
Ammonium acetate
Fused pyrimidines
α-Formyl-γ-butyrolactone
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Description
Summary:A highly efficient method was successfully developed for the synthesis of fused pyrimidines via aminoheterocyclic dihydrofuranone intermediates obtained from 2-aminoheterocycles and cyclic β-formylesters by three different methods. [Display omitted]
ISSN:0040-4020
1464-5416
DOI:10.1016/j.tet.2007.05.123