Cosmetic dermatitis in Chinese eczema patients patch tested with a modified European standard series of allergens

The prevalence of cosmetic allergic contact dermatitis (CACD) in Chinese eczema patients (CEP) has not been reported. The purpose of our study was to analyse CACD in CEP and examine the frequency of patch test (PT) reactions to common cosmetic‐related allergens (CRA). 378 consecutive CEP patch teste...

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Bibliographic Details
Published in:Contact dermatitis 2005-12, Vol.53 (6), p.314-319
Main Authors: Wang, Wen-Hui, Li, Lin-Feng, Lu, Xue-Yan, Wang, Jing
Format: Article
Language:English
Subjects:
Adult
Age Distribution
Allergens
allergic contact dermatitis
Allergic diseases
Biological and medical sciences
China - epidemiology
Chinese
Coloring Agents - adverse effects
cosmetics
Cosmetics - adverse effects
Dermatitis, Allergic Contact - diagnosis
Dermatitis, Allergic Contact - epidemiology
Dermatitis, Allergic Contact - etiology
Domestic and cosmetic products toxicology
Female
fragrance mix
Humans
Immunopathology
Logistic Models
Male
Medical sciences
para-phenylenediamine
patch test
Patch Tests - methods
Phenylenediamines - adverse effects
Preservatives, Pharmaceutical - adverse effects
prevalence
Sex Distribution
Skin allergic diseases. Stinging insect allergies
Toxicology
Urea - adverse effects
Urea - analogs & derivatives
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Summary:The prevalence of cosmetic allergic contact dermatitis (CACD) in Chinese eczema patients (CEP) has not been reported. The purpose of our study was to analyse CACD in CEP and examine the frequency of patch test (PT) reactions to common cosmetic‐related allergens (CRA). 378 consecutive CEP patch tested with a modified European standard series of allergens during a 2‐year period in our clinic were analysed. 73 patients (19.3%) were considered as suspected CACD and 37 patients (9.8%) were confirmed. The frequencies of the positive PT reactions in suspected CACD and confirmed CACD to at least 1 CRA were 64.4% and 89.2%, to para‐phenylenediamine (PPD) were 31.5% and 59.5%, to fragrance mix (FM) were 27.4% and 32.4% and to imidazolidinylurea were 5.5% and 8.1%, respectively. These results were much higher than those of CEP without cosmetic reactions (26.3% for at least 1 CRA, 5.8% for PPD, 8.8% for FM, and 0 for imidazolidinylurea) (P 
ISSN:0105-1873
1600-0536
DOI:10.1111/j.0105-1873.2005.00717.x