Reversible and Sensitive Hg2+ Detection by a Cell-Permeable Ytterbium Complex

A cell-permeable ytterbium complex shows reversible binding with Hg2+ in aqueous solution and in vitroby off–on visible and NIR emission. The fast response and 150 nM sensitivity of Hg2+ detection is based upon FRET and the lanthanide antenna effect. The reversible Hg2+ detection can be performed in...

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Bibliographic Details
Published in:Inorganic chemistry 2018-01, Vol.57 (1), p.120-128
Main Authors: Bao, Guochen, Zha, Shuai, Liu, Zhenyu, Fung, Yan-Ho, Chan, Chi-Fai, Li, Hongguang, Chu, Pak-Ho, Jin, Dayong, Tanner, Peter A, Wong, Ka-Leung
Format: Article
Language:English
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Summary:A cell-permeable ytterbium complex shows reversible binding with Hg2+ in aqueous solution and in vitroby off–on visible and NIR emission. The fast response and 150 nM sensitivity of Hg2+ detection is based upon FRET and the lanthanide antenna effect. The reversible Hg2+ detection can be performed in vitro, and the binding mechanism is suggested by NMR employing the motif structure in a La complex and by DFT calculations.
ISSN:0020-1669
1520-510X
DOI:10.1021/acs.inorgchem.7b02243