Heart Failure and Ischemic Heart Disease in Patients With Rheumatoid Arthritis

The aim of this population-based, cohort comparison study, based on all patients diagnosed with RA in Denmark over a 21-year period, was to determine the prevalence of HF and IHD before and the incidence after the established RA diagnosis.[...]we compared patients with RA versus age- and sex-matched...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2017-12, Vol.70 (24), p.3069-3071
Main Authors: Løgstrup, Brian B., Ellingsen, Torkell, Pedersen, Alma B., Kjærsgaard, Anders, Bøtker, Hans Erik, Maeng, Michael
Format: Article
Language:English
Subjects:
Age
Arthritis
Arthritis, Rheumatoid - complications
Cardiology
Cardiovascular disease
Comorbidity
Coronary artery disease
Female
Global Health
Health risk assessment
Heart diseases
Heart failure
Heart Failure - epidemiology
Heart Failure - etiology
Humans
Incidence
Ischemia
Male
Middle Aged
Myocardial Ischemia - epidemiology
Myocardial Ischemia - etiology
Patients
Rheumatoid arthritis
Risk Assessment - methods
Risk Factors
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Summary:The aim of this population-based, cohort comparison study, based on all patients diagnosed with RA in Denmark over a 21-year period, was to determine the prevalence of HF and IHD before and the incidence after the established RA diagnosis.[...]we compared patients with RA versus age- and sex-matched persons from the general population without RA.Crude and adjusted proportional subdistribution hazards ratios (sHRs) with 95% confidence intervals (CIs) accounting for competing risk of death were calculated to assess the risk of HF and IHD by comparing patients with RA and the comparison cohort without RA in a pre-defined 0 to 10-year time period after the index date.[...]RA patients have a similar prevalence of HF and IHD before the RA diagnosis as a matched comparison cohort, but patients with RA are at increased risk of HF and IHD up to 10 years after a diagnosis of RA. 1 S.E. Gabriel, Heart disease and rheumatoid arthritis: understanding the risks, Ann Rheum Dis, Vol. 69, Iss.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2017.10.028