SPG7 with parkinsonism responsive to levodopa and dopaminergic deficit

We report a 55-year-old woman with a long history of a gait disturbance that was followed by dysarthria and urinary incontinence. She underwent brain MRI, SPECT with TRODAT imaging and whole-exome sequencing, revealing the diagnosis of SPG7. She developed parkinsonism responsive to levodopa, expandi...

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Bibliographic Details
Published in:Parkinsonism & related disorders 2018, Vol.47, p.88-90
Main Authors: Pedroso, José Luiz, Vale, Thiago Cardoso, Bueno, Fabiana Lucas, Marussi, Victor Hugo Rocha, Amaral, Lázaro Luís Faria do, França, Marcondes C, Barsottini, Orlando G
Format: Report
Language:English
Online Access:Get full text
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Summary:We report a 55-year-old woman with a long history of a gait disturbance that was followed by dysarthria and urinary incontinence. She underwent brain MRI, SPECT with TRODAT imaging and whole-exome sequencing, revealing the diagnosis of SPG7. She developed parkinsonism responsive to levodopa, expanding the phenotype of complex SPG7.
ISSN:1873-5126
DOI:10.1016/j.parkreldis.2017.12.004