Myxopapillary Ependymoma of Lumbar Soft Tissue: A Case Report With Gene Expression Evaluation

Primary extraspinal myxopapillary ependymoma (MPE) is an exceptionally rare lesion that is mainly located in the subcutaneous sacrococcygeal region. We describe the first case of MPE that presented as an intramuscular tumor mass located in the lumbar area. Absence of the visible connection with the...

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Bibliographic Details
Published in:International journal of surgical pathology 2018-06, Vol.26 (4), p.364-369
Main Authors: Shelekhova, Ksenya V., Egorenkov, Vitaly V., Kheinstein, Valery A., Konstantinova, Anastasia M., Iyevleva, Aglaya, Imyanitov, Evgeny N., Matsko, Marina V., Matsko, Dmitry E.
Format: Article
Language:English
Subjects:
Case reports
Gene expression
Tumors
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Summary:Primary extraspinal myxopapillary ependymoma (MPE) is an exceptionally rare lesion that is mainly located in the subcutaneous sacrococcygeal region. We describe the first case of MPE that presented as an intramuscular tumor mass located in the lumbar area. Absence of the visible connection with the spinal cord and lack of any other tumors in the reported case argue for the primary ectopic origin of the MPE. The differential diagnosis of MPE is discussed. Additionally, we evaluated the expression level of molecular biomarkers that have a prognostic value in central nervous system tumors.
ISSN:1066-8969
1940-2465
DOI:10.1177/1066896917748195