ATLANTIC DIP: Despite insulin therapy in women with IADPSG diagnosed GDM, desired pregnancy outcomes are still not achieved. What are we missing?

To assess if pregnancy outcomes for women with GDM treated with insulin (GDM-I) are comparable to outcomes for women with GDM treated with medical nutritional therapy (MNT) (GDM-M). This retrospective cohort study included 752 women with GDM-I and 567 women with GDM-M. Maternal and foetal outcomes w...

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Bibliographic Details
Published in:Diabetes research and clinical practice 2018-02, Vol.136, p.116-123
Main Authors: Bogdanet, Delia, Egan, Aoife, Reddin, Catriona, Kirwan, Breda, Carmody, Louise, Dunne, Fidelma
Format: Article
Language:English
Subjects:
IADPSG
Insulin
Medical nutritional therapy, gestational diabetes
Pregnancy outcomes
Weight gain
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Summary:To assess if pregnancy outcomes for women with GDM treated with insulin (GDM-I) are comparable to outcomes for women with GDM treated with medical nutritional therapy (MNT) (GDM-M). This retrospective cohort study included 752 women with GDM-I and 567 women with GDM-M. Maternal and foetal outcomes were examined. Women with GDM-I had a greater risk of polyhydramnios (aOR 2.33, 95%CI 1.31–4.14) and were more likely to deliver by caesarean section (CS) (aOR 1.67, 95%CI 1.25–2.23). Their offspring had higher rates of macrosomia (22.2% vs 12.7%; p 
ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2017.12.003