Characterization, antimicrobial and antioxidant property of exopolysaccharide mediated silver nanoparticles synthesized by Streptomyces violaceus MM72

•Synthesized a novel and biologically active silver nanoparticles using exopolysaccharides of Streptomyces violaceus MM72.•S. violaceus MM72 EPS found to consist of major sugar backbones such as α-D-galactopyranose, glucose, galactose and Rhamnose.•Exopolysaccharide mediated SNPs were observed with...

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Bibliographic Details
Published in:Carbohydrate polymers 2018-02, Vol.181, p.752-759
Main Authors: Sivasankar, Palaniappan, Seedevi, Palaniappan, Poongodi, Subramaniam, Sivakumar, Murugesan, Murugan, Tamilselvi, Sivakumar, Loganathan, Sivakumar, Kannan, Balasubramanian, Thangavel
Format: Article
Language:English
Subjects:
Biological activity
Exopolysaccharide
Marine actinobacteria
Silver nanoparticles
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Summary:•Synthesized a novel and biologically active silver nanoparticles using exopolysaccharides of Streptomyces violaceus MM72.•S. violaceus MM72 EPS found to consist of major sugar backbones such as α-D-galactopyranose, glucose, galactose and Rhamnose.•Exopolysaccharide mediated SNPs were observed with enhanced antioxidant property.•Promising antibacterial activity observed with the EPS mediated SNPs against clinical isolates. Green synthesis of silver nanoparticle (SNPs) has gained considerable attention in nano-biotechnology and nano-medicine owing their potency and eco-friendliness. In this, we account the exopolysaccharide and its mediated synthesis of SNPs and their biological activities. Exopolysaccharide of the Streptomyces violaceus composed of total carbohydrate (61.4%), ash (16.1%), moisture content (1.8%) and NMR confirmed their structural composition. SNPs synthesized by the exopolysaccharide, confirmed using UV–vis spectral analysis and characterized by TEM and XRD analyses. Further, the SNPs evaluated for its antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis using disc diffusion method. The SNPs has shown promising antibacterial activity were evaluated for MIC. Furthermore, the SNPs were tested for antioxidant activities and was found to have promising antioxidant activity over the standards. The above results prove that SNPs can be considered as a potent antibacterial and antioxidant drug in future.
ISSN:0144-8617
1879-1344
DOI:10.1016/j.carbpol.2017.11.082