Standardized feeding and probiotic supplementation for reducing necrotizing enterocolitis in preterm infants in a resource limited set up

Background/objectives Necrotizing enterocolitis (NEC ≥ Stage II) is associated with high mortality and morbidity in preterm infants. To assess if introduction of standardized feeding regimen (SFR) and routine probiotic supplementation (RPS) was associated with reduced incidence of NEC in preterm inf...

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Bibliographic Details
Published in:European journal of clinical nutrition 2018-02, Vol.72 (2), p.281-287
Main Authors: Patel, Saurabh, Chaudhari, Mayur, Kadam, Sandeep, Rao, Shripada, Patole, Sanjay
Format: Article
Language:English
Subjects:
692/699/1503/1581
692/700/1720
Birth Weight
Care and treatment
Clinical Nutrition
Cohort Studies
Diet therapy
Dietary Supplements
Digestive system research
Enterocolitis
Enterocolitis, Necrotizing - epidemiology
Enterocolitis, Necrotizing - prevention & control
Epidemiology
Feeding
Feeding Methods
Female
Food and nutrition
Gastrointestinal diseases
Gestation
Gestational Age
Humans
Incidence
India - epidemiology
Infant Formula
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases - epidemiology
Infant, Premature, Diseases - prevention & control
Infants
Internal Medicine
Male
Medicine
Medicine & Public Health
Metabolic Diseases
Milk, Human
Morbidity
Mortality
Multivariate analysis
Necrosis
Necrotizing enterocolitis
Newborn babies
Patient outcomes
Pregnancy
Premature babies
Premature infants
Probiotics
Probiotics - administration & dosage
Public Health
Retrospective Studies
Supplements
Treatment Outcome
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Summary:Background/objectives Necrotizing enterocolitis (NEC ≥ Stage II) is associated with high mortality and morbidity in preterm infants. To assess if introduction of standardized feeding regimen (SFR) and routine probiotic supplementation (RPS) was associated with reduced incidence of NEC in preterm infants in our nursery in a resource limited set up. Subjects/methods This was a retrospective cohort study assessing the incidence of NEC ≥ Stage II before (Epoch 1: N  = 144) vs. after (Epoch 2, N  = 144) implementation of SFR and RPS in preterm infants 
ISSN:0954-3007
1476-5640
DOI:10.1038/s41430-017-0040-7